Day 14: The Skeleton
Developing Skeletons

Compare these two images. Both are stained with
alizarin red to show the calcification of their
bones. The image on the right is a 4 day old
rat. The one on the left is a 40 day old cat
fetus. Notice how much more calcification has taken
place in the 4 day old rat. The primary centers of
ossification extend much farther from the centers of
its long bones than those of the cat. Also notice
that primary centers of ossification have appeared
in the phalanges (toes) of the rat; they are not yet
present in the cat fetus. Could the structure
indicated by the black arrow (near the rat's elbow)
be a secondary ossification site of the humerus?
Text by Janet Sinn-Hanlon and Jo Ann Eurell
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